DIOSMIN MIXTURE

Why mixture

In practice, Diosmin is largely used in combination of Hesperidin. In one study, researchers in twenty-three countries studied diosmin as a treatment for varicose veins in over 5,000 patients. This study found that just 500 mg of a mixture of 10% hesperidin and 90% diosmin called Daflon was enough to prevent the worst complications of varicose veins, such as heaviness in the legs, inability to stand more than a few minutes, blood clots, and breakdown of the fatty layers underneath the skin of the legs. A second study found that 1000 mg of Daflon a day (two 500-mg tablets) was enough to heal leg ulcers-which are normally hard to heal and prone to infection. Since then,the mixture of 10% hesperidin and 90% diosmin has been widely used in many countries whatever as a dietary supplement or as a medicinal formulation.

In today’s market, there are also some other branded ingredients such as Diosmin Complex,Diosvein and Diosmin 95, even Diosmin+HMC, Diosmin is indeed used in combination with other citrus bioflavonoids. However, we can supply Diosmin itself and the mixture of Diosmin and Hesperidine or Diosmin and HMC (Hesperidin Methyl Chalcone) which are manufactured by ourselves.

Why micronized

Micronization means that the active ingredients of the mixture undergoes a high-tech grinding process with a jet of air at supersonic velocities, reducing the size of standard particles.Thanks to its micronized form, the mixture has a better and faster absorption, and thus an increased bioavailability, which leads to faster and more powerful clinical efficacy in venous disease.

Due to this reason, most of customers require micronized product from us instead of a normal powder (80 mesh). And we can do micronization at our own site according to the customers’ requirements and the minimum size is  less than 5 µm.

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